530 - The Association between Sleep Duration and Cardiometabolic Risk among Children and Adolescents in the United States (U.S.)

Poster Number: 530
Publication Number: 530.239

Timothy S. Morgan, Cohen Children's Medical Center, locust valley, NY, United States; Abby Basalely, Cohen Children's Medical Center, New Hyde Park, NY, United States; Pamela Singer, Long Island Jewish Medical Center, New Hyde Park, NY, United States; Laura Castellanos Reyes, Cohen Children's Medical Center, New Hyde Park, NY, United States; Christine Sethna, Cohen Children's Medical Center, New Hyde Park, NY, United States

Background: Growing evidence suggests that lifestyle factors in childhood and adolescence have a significant impact on the development of cardiometabolic diseases in adulthood. Despite this, chronic sleep deprivation has increased disproportionately in the U.S. pediatric population in recent years.

Objective: The aims were to determine the association of sleep duration with cardiometabolic risk (adiposity, blood pressure, lipids, albuminuria and A1C) and to investigate which lifestyle factors (physical activity, light exposure, caffeine consumption and sugar consumption) are associated with sleep duration in children.

Design/Methods: A nationally representative sample of children and adolescents ages 6-17 years enrolled in NHANES from 2011-2014 were included in this cross-sectional study. Sleep duration was defined as the average hours of sleep over 7 days as measured by a physical activity monitor (PAM). PAM measurements without valid data for ≥ 95% of the study period were excluded. Regression models were adjusted for age, sex, race, body mass index (BMI) Z-score (except for BMI model), physical activity and light exposure in order to assess the association of sleep with cardiometabolic risk.

Results: Among children and adolescents (mean age 11.5 years SE 0.09), average daily time spent asleep was (7.35 hours SE 0.03). Adjusted regression models found that shorter sleep duration was associated with greater SBP index (β = -3.63*10-5, 95% CI -6.99*10-5, -2.78*10-6, p = 0.035) and greater BMI Z-score (β = -0.001, 95% CI -0.001, 0.000, p = 0.002). Logistic regression models found that shorter sleep duration was associated with greater odds of obesity (OR = 0.998, 95% CI 0.997, 0.999, p < 0.001) and overweight (OR = 0.998, 95% CI 0.997, 0.999, p = 0.004). No statistically significant associations were found between sleep and measures of blood lipids, insulin sensitivity or albuminuria. Greater light exposure (β = 6.64*10-5, 95% CI 3.50*10-5, 9.69*10-5, p < 0.001) and more physical activity (β = 0.005, 95% CI 0.004, 0.006, p < 0.001) were associated with longer sleep duration.Conclusion(s): Shorter sleep duration was associated with greater blood pressure and body fat measures in children and adolescents. Improving sleep quality by increasing physical activity and light exposure in childhood may decrease the lifetime risk of developing cardiometabolic disease.
Timothy_Morgan_CV_"Association.between.Sleep.Duration.and.Cardiometabolic.Risk"TSMRESUMEFall2021.pdf