2385 - Transfusion Anemia eXpert Initiative - Control/Avoidance of Bleeding (TAXI-CAB) - Plasma and Platelet Transfusion Guidance

Sunday, April 24, 2022

10:00 AM – 11:30 AM US MT

Location: Convention Center: Mile High Ballroom 2C

CE: Live CME: 1.5

Course Number: 2385

Chair(s)

Robert Parker, MD

Professor Emeritus, Pediatric Hematology/Oncology
Stony Brook Renaissance School of Medicine
EASTON, Maryland, United States

Participants should be aware of the following financial/non-financial relationships:

Robert I. Parker, MD: I do not have any relevant financial / non-financial relationships with any proprietary interests.

Plasma and platelet transfusions are frequently prescribed to critically ill children who are actively bleeding or at risk of bleeding. Despite their possible therapeutic benefits, both plasma and platelet transfusions have been independently associated with significant morbidity and mortality. Given the significant dangers, guidelines must be available to help intensivists weigh the risks and benefits to their patients. The Transfusion and Anemia eXpert Initiative – Control/Avoidance of Bleeding (TAXI-CAB), in collaboration with the Pediatric Critical Care Blood Research Network (BloodNet), the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI), the Society for the Advancement of Blood Management (SABM), the Network for the Advancement of blood management, Haemostasis and Thrombosis (NATA), the International Society of Blood Transfusions (ISBT) and the Society for Critical Care Medicine (SCCM), created a comprehensive series of consensus statements via an organized and structured process outlining existing data and future research foci in the area of plasma and platelet transfusions in critically ill children. TAXI-CAB seeks to provide evidence-based guidance for pediatric intensivists to encourage the use of plasma and platelet transfusions in the right scenarios to maximize their clinical benefit and minimize their harm.

The following topics will be covered in this session: (1) general overview; (2) children following cardiopulmonary bypass or on extracorporeal membrane oxygenation; (3) children with cancer; (4) children following non-cardiac surgery; and (5) research priorities.

Presentations:

10:00 AM – 10:15 AM US MT

Executive Summary of Recommendations and Expert Consensus for Plasma and Platelet Transfusions in Critically Ill Children
Speaker: Robert I. Parker, MD – Stony Brook Renaissance School of Medicine
10:15 AM – 10:30 AM US MT

Plasma and Platelet Transfusion Strategies in Critically Ill Children with Malignancy
Speaker: Lani Lieberman, MD, BSc – University Health Network
10:30 AM – 10:45 AM US MT

Invasive Procedures and Non Cardiac Surgery
Speaker: Marisa Tucci, MD – Universite de Montreal Faculty of Medicine
10:45 AM – 11:00 AM US MT

Plasma and Platelet Transfusion Strategies in Children Following Cardiopulmonary Bypass Surgery or Supported by ECMO
Speaker: Jill M. Cholette, MD – Golisano Children's Hospital at The University of Rochester Medical Center
11:00 AM – 11:15 AM US MT

Research Priorities in Plasma and Platelet Transfusions for Critically Ill Children
Speaker: Kenneth Remy, MD, MHSc, MSCI, FCCM – Case Western Reserve University School of Medicine