545 - PAS Postgraduate Course - Neonatal Nutrition and Gastrointestinal Physiology: Gaps in the evidence to inform clinical practice

Friday, April 22, 2022

9:00 AM – 2:30 PM US MT

Location: Convention Center: 207

CE: Live CME: 5.5

Course Number: 545

Chair(s)

Sarah Taylor, MD, MSCR (she/her/hers)

Professor
Yale University
MADISON, Connecticut, United States

Participants should be aware of the following financial/non-financial relationships:

Sarah N. Taylor, MD, MSCR: ● Astarte Medical (Ended In the Past 24 Months) (Products/Services: Speaker Honorarium including speakers bureau, symposia, and expert witness)
● Ferring Pharmaceuticals (Currently Ongoing) (Products/Services: Research Support including clinical trials & the principal or named investigator)
● Pfizer (Currently Ongoing) (Products/Services: Research Support including clinical trials & the principal or named investigator)
● Prolacta Bioscience (Currently Ongoing) (Products/Services: Research Support including clinical trials & the principal or named investigator)

Emphasis on the impact of nutrition in preterm infant health and neurodevelopment has led to greater attention to the subtleties of nutrition delivery. Clinical approaches such as optimization of macronutrient delivery, prioritization of enteral nutrition, and enhanced growth monitoring have evolved from this research. Yet, dilemmas persist, and new problems have arisen. Necrotizing enterocolitis remains a significant risk, and the potential for enteral nutrition exposures to mitigate or exacerbate this risk remain a critical conundrum. Following previous recognition of the extreme growth faltering of preterm infants, deficits in nutrient delivery have diminished, but a balancing measure, the potential for excessive nutrition, requires attention. Nutritional product options have expanded, but, for many of these, greater research is needed to inform clinical application. Through this postgraduate course, six neonatal researchers will detail the evidence supporting clinical nutritional interventions with a focus on where further research is needed. Evidence-based approaches and the gaps that persist will be detailed for preterm infant growth (Dr. Sarah Taylor), protein intake (Dr. Laura Brown), and fat intake (Dr. Camilia Martin). Current evidence regarding gastrointestinal physiology and how it relates to feeding will be covered by an overview of necrotizing enterocolitis (Dr. Misty Good), feed initiation and advancement (Dr. Brenda Poindexter) and options in enteral nutrient delivery (Dr. Hair). Two panel sessions will be held. One is an opportunity to ask about academic career advancement with Drs. Brown, Good, and Poindexter. The second will focus on approaches to nutrition research with Drs. Hair, Martin, and Taylor.

Presentations:

9:00 AM – 2:30 PM US MT

A bench-to-bedside approach to studying gastrointestinal physiology in NEC
Speaker: Misty Good, MD, MS – University of North Carolina at Chapel Hill School of Medicine
9:00 AM – 2:30 PM US MT

Implementation of Standardized Feeding Protocols in the NICU to Reduce NEC and Optimize Outcomes
Speaker: Brenda Poindexter, MD MS – Emory University and Children's Healthcare of Atlanta
9:00 AM – 2:30 PM US MT

Incorporating fat in the preterm diet: Evidence-based practices and setting the research agenda
Speaker: Camilia Martin, MD, MS – Beth Israel Deaconess Medical Center/Harvard Medical School
9:00 AM – 2:30 PM US MT

Optimization of enteral nutrition to promote growth in preterm infants
Speaker: Amy B. Hair, MD – Baylor College of Medicine
9:00 AM – 2:30 PM US MT

Preterm infant growth: The more we learn, the more we need to learn
Speaker: Sarah N. Taylor, MD, MSCR – Yale University
9:00 AM – 2:30 PM US MT

Targeting protein delivery in enteral and parenteral nutrition
Speaker: Laura D. Brown, MD – University of Colorado School of Medicine